Andra livgrenadjärregementet (2nd Life Grenadier Regiment), designation I 5, was a Swedish Armyinfantryregiment that traced its origins back to the 16th Century. It was merged into a new regiment in 1927. The regiment's soldiers were recruited from the province of Östergötland.
The regiment was allotted in 1687. The regiment was given the designation I 5 (5th Infantry Regiment) in a general order in 1816. Andra livgrenadjärregementet was then merged with Första livgrenadjärregementet in 1928 to reform the old Livgrenadjärregementet.